Problem uploading

Can anyone help with this... I can't get my files to upload and get the following error message...

[22:04:45] Remote file exist check: "index.html".
[22:04:45] TYPE I
[22:04:46] 200 Type set to I.
[22:04:46] SIZE index.html
[22:04:48] 550 index.html: No such file or directory
[22:04:48] PASV
[22:04:49] 227 Entering Passive Mode (212,67,199,117,19,123).
[22:04:49] Opening data connection to 212.67.199.117 Port: 4987
[22:04:49] STOR index.html
[22:04:50] 550 index.html: Permission denied
[22:04:50] Transfer failed.
[22:04:50] TYPE A
[22:04:51] 200 Type set to A.
[22:04:51] PASV
[22:04:52] 227 Entering Passive Mode (212,67,199,117,19,124).
[22:04:52] Opening data connection to 212.67.199.117 Port: 4988
[22:04:52] LIST -aL
[22:04:55] 150 Opening ASCII mode data connection for file list
[22:04:55] 226 Transfer complete.
[22:04:59] 209 bytes transferred. (40 bytes/s) (00:00:05)
[22:05:49] NOOP
[22:05:50] 200 NOOP command successful.
[22:06:13] Remote file exist check: "ed.html".
[22:06:13] TYPE I
[22:06:14] 200 Type set to I.
[22:06:14] SIZE ed.html
[22:06:15] 550 ed.html: No such file or directory
[22:06:15] PASV
[22:06:17] 227 Entering Passive Mode (212,67,199,117,19,125).
[22:06:17] Opening data connection to 212.67.199.117 Port: 4989
[22:06:17] STOR ed.html
[22:06:18] 550 ed.html: Permission denied
[22:06:18] Transfer failed.
[22:06:18] TYPE A
[22:06:19] 200 Type set to A.
[22:06:19] PASV